Dose-response Modeling Applications In Field Of Environmental Health

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Modeling of dose-response relationships.

The main dose-response models for chronic toxicity are considered. For dichotomous response, the log probit, multi-hit, and multistage models are presented. For time-to-occurrence response, the log-normal and three variations of multistage models are presented. Finally, the Cornfield hockey-stick model is considered, and, for low-dose extrapolation, it is suggested that response be taken to be ...

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ژورنال

عنوان ژورنال: Journal of Mathematics and Computer Science

سال: 2014

ISSN: 2008-949X

DOI: 10.22436/jmcs.09.04.16